Dr. Fritz Böhler is a prisoner of war doctor in the Soviet POW camp 5110/47 near Stalingrad. Despite the harshest conditions, he tries to help his fellow prisoners with the simplest means. But when his assistant Dr. Schultheiss falls in love with the Russian doctor Alexandra Kasalinskaja, Schultheiss not only endangers his own life - because Alexandra is the lover of First Lieutenant Markow.